Tags: cardiovascular health, cholesterol, ldl, resveratrol benefits, Resveratrol Heart Health Benefits
A year 2000 report coordinated by Jiangang, Zou, Yuanzhu Huang, Qi Chen, Enhui Wei, Keijiang Cao, and Joseph M. Wu investigated the effects of resveratrol on low density proteins (LDL) also known as the “bad cholesterol.” This team of researchers tested resveratrol on LDLs using two different oxidation systems.
LDLs were isolated from the plasma of two groups of volunteers. Half of these volunteers’ LDLs were oxidized using Cu(2)-induced oxidation and the other half were oxidized with an Azo compound. In both cases, resveratrol doses were added at different concentrations. Any modifications to their LDL levels resulting from the resveratrol dosage were then monitored.
Effects of Resveratrol on LDLs
The LDLs that were oxidized using Cu(2) experienced a 70.5% reduction in TBARS (Thiobarbituric Acid). Higher concentrations had a greater effect on reduction of TBARS than lower doses did.
In these samples, relative electrophoretic mobility (REM) was reduced by 42.3% and macrophage (white blood cell) degradation by 65.7%.
Use of the LDLs oxidized by the Azo compound were intended to further validate the findings in the Cu(2) oxidized LDLs.
Conclusions of Resveratrol Study
The results of this study show that red wine esveratrol has a significant impact on the bad cholesterol lipoproteins that cause plaque build up in arteries.
The use of resveratrol interrupted known reactors in LDLs that cause the build up of plaque and eventual heart disease. Thus, resveratrol is a viable prevention mechanism for heart disease.