Tags: antiaging, caloric restriction, resveratrol, resveratrol benefits
In 2008, Jason G. Wood, Siva Lavu, and David Sinclair of the Department of Pathology at Harvard Medical School in Boston; Blanka Rogina and Stephen L. Helfand of the Department of Genetics and Developmental Biology at the University of Connecticut Health Center in Farmington; Konrad Howitz of Biomol Research Laboratories in Plymouth Meeting, Pennsylvania; and Marc Tatar of the Department of Ecology and Evolutionary Biology at Brown University in Providence, Rhode Island conducted a study on Sirtuin activating compounds and their life extending properties on animals due to their replication of the properties of caloric restriction.
Particulars of the Study
Caloric restriction extends lifespan in numerous species. Sirtuin activating compounds (STACs) can promote the survival of human cells and extend the lifespan of yeast. Because resveratrol can significantly extend lifespan in yeast the study analyzed whether it could also extend lifespan in other animals like worms and flies.
Key Findings for Life Extention
The study demonstrated that red wine resveratrol and other Sirtuin activating compounds activate sirtuins from a species of worm (Caenorhabditis elegans) and a species of fly (Drosophila melanogaster)and extend the lifespan of these animals without reducing their ability to reproduce.