Antioxidant Resveratrol Protects Against DNA Damage Caused by Kidney Carcinogens
The Department of Animal Biology-II (Animal Physiology) and the Faculty of Biology at the Compultense University in Madrid, Spain, Drs. S. Cadenas and G. Baria released a study in 1999 reporting that resveratrol, a red wine ingredient, can protect against DNA damage induced by a kidney cancer-causing substance.
Antioxidants melatonin, vitamin E, and resveratrol have free radical scavenger properties that can decrease the damaging effects of free radicals in the environment. These antioxidants can provide preventative and therapeutic advantages.
The research shows that resveratrol completely depleted a dangerous kidney carcinogen and was partially depleted by melatonin and vitamin E. The study also showed that administering a resveratrol dosage prevented an increase in relative kidney weight induced by the cancer-causing agent.
The results proved that resveratrol, among other antioxidants, and a free radical trap can prevent oxygen induced DNA damage in the kidney by the experiment’s cancer causing agent, or carcinogen.